Know if it's good, bad or indifferent?

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Originally posted by choccrackles:
http://www.hamishmcnally.com
you probably all know his site by now VBG

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Yeah,

But I can't seem to find an update as tyo how he's doing on the bloody thing anymore. Has it gotten more crowded or is my chemo brain still more worrisome than I thought?

IOW, how's Ham doing? BTW, this must the first time I went on his site with my sound on. Someone might think ya'll are Scotish or something. <g>

I've never heard of this, but this is what it says about a similar disorder on medterms.com:

"Syndrome, giant platelet (Bernard-Soulier syndrome):

This condition is a primary problem of platelets in which the platelets lack the ability to stick adequately to injured blood vessel walls and as a result of this problem there is abnormal bleeding.

The giant platelet syndrome usually presents in the newborn period, infancy, or early childhood with bruises, nose bleeds (epistaxis), and/or gum (gingival) bleeding. Later problems can occur with anything which can induce bleeding such as menstruation, trauma, surgery, or stomach ulcers.

This is an inherited disease transmitted in an autosomal recessive pattern. Both parents must carry a gene for the giant platelet syndrome and transmit that gene to the child for the child to have the disease. The molecular basis is known and is due to a deficiency in platelet glycoproteins Ib, V, and IX. The parents have a decrease in the glycoprotein but no impairment of platelet function and no abnormal bleeding. The gene responsible for the syndrome has been mapped to the short (p) arm of chromosome 17.

There is no specific treatment for the giant platelet syndrome. Bleeding episodes may require platelet transfusions.

The abnormal platelets in the Bernard-Soulier syndrome are usually considerably larger than normal platelets when viewed on blood films or sized by automated instruments. However, this is not the only syndrome with large platelets. Specific platelet function tests as well as tests for the glycoproteins can confirm the diagnosis.

This disease was first recognized in 1948 by two French hematologists, Jean Bernard and Jean-Pierre Soulier, and so is also known as the Bernard-Soulier syndrome."

Hope that helps,

-Larry

PS: Thank you for the emails.

So far as I know this isn't a condition. It's just something that's shown up in the two CBC's I had last week. They were only two days apart because of the holiday, so I'd be surprised if they had actually disappeared.

Just curious about the term. My doc saw the tests and said I was doing great.

Thanks so much for looking that up for me!

Great! It sounds like Janice's doc with her platelet count that refused to rise. The doctor wasn't concerned in light of good BMBs and other counts. She said she wasn't concerned and that's what you want to hear from a doctor

Tex,
I don't know if this helps, I suspect it won't but I found this great article which gives great shots and breakdowns on all the FAB sub-grps....interesting reading...there was one spot referring to "giant platelets" but no real mention of what they are...gathered it was "secret doc talk" or something??

As for Ham...(who is not scottish by any means...we're 6th generation downunder...but there might be some throwback lineage somewhere) he's doing great...off to America Sunday for a month...yes i am already booked for counselling!!! I went into panic mode last week when they had trouble pulling his blood thinking oh no! it must be too viscous!! ie.relapse. but it was just me panicking. Thx for asking and I'm sorry that you can't load his updates...but hey I ain't no tech guru...just like fooling around with his site.

quote:

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Originally posted by choccrackles:
I don't know if this helps, I suspect it won't but I found this great article which gives great shots and breakdowns on all the FAB sub-grps....interesting reading...there was one spot referring to "giant platelets" but no real mention of what they are...gathered it was "secret doc talk" or something??

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Yeah, it helps if one understands the language. I never feel so lost in English as when trying to decipher a scientific document. But I sure appreciate you sharing it!

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As for Ham...(who is not scottish by any means...we're 6th generation downunder...but there might be some throwback lineage somewhere)

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With a name like McNally, I think there's got to be some Scots back there somewhere. I was just refering to the music. Usually hear it on bagpipes.

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he's doing great

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Yay!

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off to America Sunday for a month ...yes i am already booked for counselling!!!

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I gotta ask "why" for both statements?

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Thx for asking and I'm sorry that you can't load his updates...but hey I ain't no tech guru...just like fooling around with his site.

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I couldn't find them. I just went and looked under "miletones." Voila!

Have a safe trip.

quote:

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Originally posted by choccrackles:
the counselling will be for me I think because a whole month without Hamish might be a bit hard on us...

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Ah! I didn't get that he was going without ya'll. I get it now.

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Originally posted by choccrackles:
what a b****y mouthful you might think...

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Took me a moment to figure out what b****y meant. We in the US (don't ever call this Texas boy a "yank") don't tend to know what that word actually refers to, so we don't think of it as cussin'. So, when we use it rarely, we don't feel any compunction against spelling it out.